Division of Infectious Diseases

Sanjay Mehta, M.D.

Sanjay Mehta, M.D.
Assistant Clinical Professor

Stein Clinical Research Building, Room 408
9500 Gilman Drive # 0711
La Jolla, CA 92093

Telephone: (858) 822-4092
Fax: (858) 822-5362
Email: srmehta@ucsd.edu


Dr. Sanjay Mehtais one of the solid organ transplant infectious disease faculty at UCSD. He also maintains an HIV-HCV co-infection clinic and is an Assistant Director of the Clinical Microbiology Lab at UCSD.  He is also one of the Faculty Advisors for the UC Haiti Project.

His research interests include tropical infectious diseases and their interactions with HIV, and in particular the immunology of Leishmaniasis.

He has developed in vivo and in vitro methods to more rapidly screen anti-Leishmanial therapeutics, and has worked on vaccine development for the parasite.

He also has a strong interest in viral evolution, and how HIV evolves within an individual and a population.  Understanding how the virus evolves provides knowledge about the pathogenicity, transmission and spread of the HIV.  In particular, Dr. Mehta is working on how phylogenetic models can help us learn about ongoing epidemics, and predict how they may spread.  

Background

Education

   
8/91 - 6/95 Johns Hopkins University B.A,; Chemistry
8/95 - 5/99 Case Western Reserve University M.D.

Post Doctoral Training

 
7/99 - 6/02 University of Colorado Hospitals Internal Medicine Internship and Residency
1/02 - 3/02 London School of Tropical Medicine & Hygiene Diplomate Program in Tropical Disease and Hygiene
7/03 - 2/05 University of Maryland Fellowship, Infectious Disease
2/05 - 6/08 University of California, San Diego Fellowship, Infectious Disease

 

Selected Publications

Mehta SR, Huang RC, Yang M, Zhang XQ, Kolli B, Chang KP, Hoffman RM, Goto Y, Badaro RB, and Schooley RT. Real Time in vivo GFP Imaging in a Murine Leishmaniasis Model:  a new tool for Leishmania drug discovery. CVI 2008 Dec; 15(12) (pp1764-1770). PMID:18945882.  PMCID:  PMC2593180

Brodine SK, Thomas A, Huang R, Harbertson J, Mehta S, Leake J, Nutman T, Moser K, Wolf J, Ramanathan R, Burbelo P, Nou J, Wilkins P, Reed SL.  Community based parasitic screening and treatment of Sudanese refugees: application and assessment of Centers for Disease Control guidelines.  Am J Trop Med Hyg. 2009 Mar;80(3):425-30. PMID: 19270293

Mehta SR, MacGruder C, Looney D, Johns S, Smith DM.  Differences in Tuberculin Reactivity:  An experience from a VA Employee Health Screening Program.  CVI  2009 April; 16(4). pp541-543. PMID: 19225075.  PMCID:  PMC 2668276

Manosuthi W, Butler D, Poon A, Pond SL, Pillia SK, Mehta S, Pacold M, Richman D, Smith D.  Protease Polymorphisms in HIV-1 Subtype CRF01_AE Represent Selection by Antiretroviral Therapy and Host Immune Pressure. AIDS. 2010 Jan 28;24(3):411-6. PMID:20009919. PMCID: PMC2913588

Mehta SR, Zhang XQ, Badaro R, Spina C, Day J, Chang KP, Schooley RT Flow cytometric screening for anti-leishmanials in a human macrophage cell line.. Exp Parasitol. 2010 Dec;126(4):617-20. Epub 2010 Jun 9. PMID: 20540940.  PMCID:  PMC2939291.

Mehta S. Developing the right pneumococcal vaccine for the time and place.  Am J Trop Med Hyg. 2010 Sep;83(3):449-50. PMID: 20810802 PMCID: PMC2929033

Mehta SR, Delport W, Osorio G, Pond S, Little S, Smith D. "The Relatedness of HIV Epidemics in the United States- Mexico Border Region" AIDS Res Hum Retroviruses. 2010 Dec;26(12):1273-7. Epub 2010 Oct 26. PMID: 20977301. PMCID: PMC3011998

Mehta SR and Huang RC. ‘Parasite Infections in Transplant’. AST Transplant Infectious Disease Handbook

Cannella A, Nguyen B, Piggott C, Lee RA, Vinetz JM, Mehta SR. “A Cluster of Cutaneous Leishmaniasis Associated with Human Smuggling”. Am J Trop Med Hyg. 2011 Jun;84(6):847-50. PMID: 21633017 PMCID: PMC3110366

Mehta SR, Wertheim J, Delport W, Ene L, Tardei G, Duiculescu D, Pond S, Smith DM.  “Using Phylogeography to Characterize the Origins of the HIV-1 Subtype F Epidemic in Romania”. Infection, Genetics and Evolution. 2011 Jul;11(5):975-9. PMID:21439403. PMCID: PMC3104099

Mehta SR, Nguyen V, Osorio G, Little S, Smith DM..”Evaluation of Pooled Rapid HIV Antibody Screening in Patients Admitted to a San Diego Hospital”. J Virol Methods. 2011 Jun;174(1-2):94-8. Epub 2011 Apr 12. PMID: 21513744 PMCID: PMC3095723.

Rodrigues MZ, Grassi MF, Mehta SR, Zhang XQ, Gois L, Schooley R, Badaro R. “Th1/Th2 Cytokine profile in HIV and Leishmania co-infected Patients in Brazil”. Clin Vaccine Immunol. 2011 Aug 10. [Epub ahead of print]. PMID: 21832098

Green J, Abeles S, Uslan D, Mehta SR. Persistent Neutrophilic Meningitis in an Immunocompetent Patient after Basilar Skull Fracture. BMC Infect Dis. 2011 May 19;11:136. PMID: 21595944 PMCID: PMC3115869

Holmes EC, Ghedin E, Halpin RA, Stockwell TB, Zhang XQ, Fleming R, Davey R, Benson CA, Mehta SR, Taplitz R, Liu YT, Brouwer KC, Wentworth DE, Lin X, INSIGHT FLU002 Study Group, Schooley RT.  Extensive Geographical Mixing of Human H1N1/09 Influenza A Virus in a Single University Community. Journal of Virology. 2011 Jul;85(14):6923-9. PMID:21593168. PMCID: PMC3126550.

Kim D, Lyoo KS, Smith DM,Hur W, Hong SW, Sung PS, Yoon KS, Mehta SR. Number of Mutations Within CTL-Defined Epitopes of the HBV Core Region Are Associated with HBV Disease Progression. J Med Virol. 2011 Dec;83(12):2082-7. PMID: 22012714

Mehta SR, Pond SL, Richman D, Little S, Smith DM. “Associations between Phylogenetic Clustering and HLA Profile among HIV Infected Individuals in San Diego, California”.  J Infect Dis. 2012 May;205(10):1529-33. Epub 2012 Mar 23. PMID: 22448013

Maia, Z.P.G.1; Lírio, M.1; Mistro, S.1; Mendes, C.M.C.1; Mehta, S.R.2 and  Badaró,R. Comparative study of rK39 leishmania antigen for serodiagnosis of Visceral Leishmaniasis: Systematic Review with Meta-analysis. PLOS NTD (accepted)