Division of Infectious Diseases and Global Public Health

Julissa Trahan, BS

Research Associate II

UCSD
Department of Medicine 
Mail Code 0676
9500 Gilman Drive
La Jolla, CA 92093-0676

Telephone: (858) 552-8585 ext. 2616


Research Interests

I evaluate pharmacokinitecs and toxicology in rodents and evaluate new compounds in cell cultures for antiviral activity and cytotoxicity.

Educational Background

BS Biology San Diego State University

Selected Publications

Antiproliferative effects of octadecyloxyethyl 9-[2-(phosphonomethoxy)ethyl]guanine against Me-180 human cervical cancer cells in vitro and in vivo. Valiaeva N, Trahan J, Aldern KA, Beadle JR, Hostetler KY. Chemotherapy. 2010;56(1):54-9. Epub 2010 Mar 8.

Effect of oral treatment with hexadecyloxypropyl-[(S)-9-(3-hydroxy-2- phosphonylmethoxypropyl)adenine] [(S)-HPMPA] or octadecyloxyethyl-(S)-HPMPA on cowpox or vaccinia virus infections in mice. Quenelle DC, Collins DJ, Herrod BP, Keith KA, Trahan J, Beadle JR, Hostetler KY, Kern ER. Antimicrob Agents Chemother. 2007 Nov;51(11):3940-7. Epub 2007 Sep 10.

Synthesis of the 5-phosphono-pent-2-en-1-yl nucleosides: a new class of antiviral acyclic nucleoside phosphonates. Choo H, Beadle JR, Chong Y, Trahan J, Hostetler KY. Bioorg Med Chem. 2007 Feb 15;15(4):1771-9. Epub 2006 Nov 30.

Antiviral activities of novel 5-phosphono-pent-2-en-1-yl nucleosides and their alkoxyalkyl phosphonoesters. Choo H, Beadle JR, Kern ER, Prichard MN, Keith KA, Hartline CB, Trahan J, Aldern KA, Korba BE, Hostetler KY. Antimicrob Agents Chemother. 2007 Feb;51(2):611-5. Epub 2006 Nov 27.

Oral 1-O-octadecyl-2-O-benzyl-sn-glycero-3-cidofovir targets the lung and is effective against a lethal respiratory challenge with ectromelia virus in mice. Hostetler KY, Beadle JR, Trahan J, Aldern KA, Owens G, Schriewer J, Melman L, Buller RM.Antiviral Res. 2007 Mar;73(3):212