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Contact Dr. Fierer
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Veteran's Affairs
San Diego Healthcare System
3350 La Jolla Village Drive
Mail Code 9111-F
San Diego, CA 92161
Phone: 858-552-7446
Fax: 858-552-4398
Email: jfierer@ucsd.edu
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Research Interests
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The focus of his research is host-pathogen interactions, emphasizing Salmonella enterica and Coccidioides immitis. Most recently, his research has focused on the role of innate immunity in resistance to Salmonella infections, and on the genetic basis of resistance to coccidioidomycosis, using murine infections as model systems. Resistance genes are being mapped in mice, and the interplay between these genes and cytokine responses to infection is under investigation. Dr. Fierer is a Fellow of the Infectious Diseases Society of America, AAAS, and the American Academy of Microbiology.
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Educational Background
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1959:Columbia – B.A.
1963:New York University - M.D.
1963-1964: Grace New Haven Hospital - Internship
1966-1968: Yale New Haven HospitalResidency
1968 l969: University of Pittsburgh - Research Fellow
1969 1971: University of California, San Diego - Research Fellow
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Faculty Page
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Joshua Fierer, M.D.Michael and Marci Oxman Professor of Medicine and Pathology
Chief, Infectious Diseases Section, VA San Diego Healthcare System
Director, Microbiology Laboratory, VA San Diego Healthcare System
Click here to view Dr. Fierer's CV
Click here to view Dr. Fierer's NIH Biosketch
Dr. Fierer graduated from NYU School of Medicine and then did a residency in Internal Medicine at Yale-New Haven Hospital, sandwiched around a two year stint in the Epidemic Intelligence Service at CDC. He did his Infectious Diseases Fellowship training with Abraham Braude at the University of Pittsburgh and then at UCSD. He joined the faculty at UCSD School of Medicine as an Assistant Professor in 1971 and has remained at that institution ever since.
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Selected Publications
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1. Fierer, J., Walls, L., Eckmann, L., Yamamoto, T., and Kirkland, T. N.: Importance of interleukin-10 in genetic susceptibility of mice to Coccidioides immitis. Infect. Immun. 66:4397-4402, 1998.
2. Fierer, J., Walls, L., Kirkland, T.N.: Genetic evidence for the role of the Lv locus in early susceptibility but not IL-10 synthesis in experimental coccidioidomycosis in C57BL mice. J.Infect.Dis. 181:681-685, 2000.
3. Lesnick, M.L., Reiner, N.E., Fierer, J., and Guiney, D.G.: The Salmonella spvB virulence gene encodes an enzyme that ADP-ribosylates actin and destabilizes the cytoskeleton of eukaryotic cells. Mol. Microbiol. 39:1464-1470, 2001.
4. Fierer, J., Swancutt, M.A., Heumann, D., and Golenbock, D.: The role of lipopolysaccharide binding protein in resistance to Salmonella infections in mice. J. Immunol. 168:6396-6403, 2002.
5. Asensi, V., Valle, E., Meana, A., Fierer, J., Celada, A., Alvarez, V., Paz, J., Coto, E., Carton, J.A., Maradona, J.A., Dieguez, A., Sarasua, J., Ocana, M.G., Arribas, J.M.: In vivo interleukin-6 protects neutrophils from apoptosis in osteomyelitis. Infect.Immun. 72:3823-3828, 2004.
6. Viriyakosol, S., Fierer, J., Brown, G.D., and Kirkland, T.N.: Innate immunity to the pathogenic fungus Coccidioides posadasii is dependent on Toll-like receptor 2 and Dectin-1. Infect Immun. Mar;73(3):1553-60, 2005 .
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